Ipamorelin 2mg – 5 Vials

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$79.92

Ipamorelin – 2mg (5 Vials) 

$15.98 per vial

250 in stock

SKU: ipamorelin-2mg-5-vials Categories: , , Tags: ,

Product Usage: Our peptides are for research purposes only. All products on this site are research chemicals strictly for in vitro testing and laboratory experimentation only. Our products are not intended for human or animal medial use. All product information available on this website is for educational purposes only. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Ipamorelin – 2mg (5Vials)

History – What is Ipamorelin?

Ipamorelin is a pentapeptide (containing five different amino acids) that excretes growth hormones into the bloodstream from the anterior of the pituitary gland. This peptide mimics ghrelin (a hormone produced by enteroendocrine cells of the gastrointestinal tract) and connects with the ghrelin receptor of the brain. Its main purpose is to regulate the thyroid gland functions, reduce pain, manage body growth, and regulate body temperature.

The Benefits That These Peptides Cause Together

While Ipamorelin provides different benefits to individuals, it is better when they are taken together with CJC 1295 to maximize the amount of growth hormone being released into the body to reverse the negative effects of aging. These two peptides complement each other to create one powerful peptide to enhance the human body and cause one to feel youthful by naturally:

  • increasing muscle growth
  • decreasing body fat
  • improving sleep quality
  • rejuvenating damaged tissues
  • clearing elastosis
  • strengthening immunity

Patients who experience problems with aging, low energy, weak immune systems, or growth hormone deficiency can benefit from CJC Ipamorelin, however, those with cancerous tumors should avoid this peptide.

 

Sequence C38H49N9O5
CAS 170851-70-4
Molecular Formula C38H49N9O5
Molecular Weight 711.9g/mol
CID 9831659
Appearance White Lyophilized Powder

IpamorelinIpamorelin Peptide (Growth Hormone Releasing Peptide)

Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a synthetic pentapeptide which has distinct and specific growth hormone (GH)-releasing properties. It’s amino acid sequence is Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.

Ipamorelin triggers and stimulates Growth hormone production by mimicking the action of the natural hormone Ghrelin: In the hypothalamus binds to Ghrelin receptors), stimulates the release of Somatocrinin (also called as Growth hormone releasing hormone – GHRH) and at the same time it inhibits the amount of Somatostatin and suppresses its action.  In addition, it stimulates body weight gain in animals. Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels. However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to GHRH, ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.

Ipamorelin released GH from primary rat pituitary cells with a potency and efficacy similar to GHRP-6 (ECs) = 1.3+/-0.4nmol/l and Emax = 85+/-5% vs 2.2+/-0.3nmol/l and 100%). A pharmacological profiling using GHRP and growth hormone-releasing hormone (GHRH) antagonists clearly demonstrated that Ipamorelin, like GHRP-6, stimulates GH release via a GHRP-like receptor.

In pentobarbital anaesthetised rats, Ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80+/-42nmol/kg and Emax = 1545+/-250ng GH/ml vs 115+/-36nmol/kg and 1167+/-120ng GH/ml). In conscious swine, Ipamorelin released GH with an ED50 = 2.3+/-0.03 nmol/kg and an Emax = 65+/-0.2 ng GH/ml plasma. Again, this was very similar to GHRP-6 (ED50 = 3.9+/-1.4 nmol/kg and Emax = 74+/-7ng GH/ml plasma). GHRP-2 displayed higher potency but lower efficacy (ED50 = 0.6 nmol/kg and Emax = 56+/-6 ng GH/ml plasma).

Growth Hormone Release

The specificity for GH release was studied in swine. None of the GH secretagogues tested affected FSH, LH, PRL or TSH plasma levels. Administration of both GHRP-6 and GHRP-2 resulted in increased plasma levels of ACTH and cortisol. Very surprisingly, Ipamorelin did not release ACTH or cortisol in levels significantly different from those observed following GHRH stimulation. This lack of effect on ACTH and cortisol plasma levels was evident even at doses more than 200-fold higher than the ED50 for GH release. In conclusion, Ipamorelin is the first GHRP-receptor agonist with a selectivity for GH release similar to that displayed by GHRH.

More about Ipamorelin

  1. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/ipamorelin
  2. ScienceDirect: https://www.sciencedirect.com/topics/neuroscience/ipamorelin
  3. Wiki: https://en.wikipedia.org/wiki/Ipamorelin
Buy <h4 class="nitro-offscreen"><strong>Ipamorelin – 2mg (5 Vials) </strong></h4> <h5 class="nitro-offscreen"><strong>$15.98 </strong><strong>per vial</strong></h5> - $79.92 | Us Chem Labs | 99% Pure!

Buy Ipamorelin – 2mg (5 Vials)  $15.98 per vial - $79.92. Us Chem Labs provides the highest quality, highest purity peptides at the lowest price per milligram.

Product SKU: ipamorelin-2mg-5-vials

Product Brand: US Chem Labs

Product Currency: USD

Product Price: 72.92

Price Valid Until: 2023-12-31

Product In-Stock: InStock

Editor's Rating:
5

ALL PRODUCTS ON THIS SITE ARE INTENDED AS RESEARCH CHEMICALS ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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